en عمومى General Orginal Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:107%">Heart valve replacement surgery requires long-term care due to its chronic nature. Warfarin, as the primary post-operative medication, can lead to complications such as bleeding or embolism if there is poor adherence to the treatment. This study aimed to investigate the effect of social media-based education on the control of the International Normalized Ratio (INR) index in heart valve replacement patients.</span><br> <span style="line-height:107%">This experimental study was conducted on 104 patients under warfarin treatment who underwent heart valve replacement surgery between August 2022 and May 2023. Patients were divided into control and intervention groups. The intervention group, in addition to routine discharge education, received warfarin-related training via social media for two months and was followed up for an additional two months. The INR index was evaluated before and after the intervention, and data were analyzed using independent T-tests, paired T-tests, and Chi-square tests.</span><br> <span style="line-height:107%">The results showed that there was no significant difference in demographic variables between the two groups. The mean change in INR in the intervention group significantly decreased by -1.27 &plusmn; 0.35 after the intervention (P-value < 0.001), whereas this change was not significant in the control group (P-value = 0.18).</span><br> <span style="line-height:107%">Utilizing social media-based education can help improve quality of life and reduce warfarin complications by increasing patient awareness and treatment adherence.</span></span></span><br> &nbsp;</div> Warfarin, Social Media, Heart Valve Replacement, Patient Education 48 57 http://jrhms.thums.ac.ir/browse.php?a_code=A-10-190-1&slc_lang=en&sid=1 Fatemeh Fathi 10031947532846002248 10031947532846002248 No School of Nursing and Midwifery, Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran Ahmadreza FallahFaragheh 10031947532846002249 10031947532846002249 No School of Nursing and Midwifery, Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran Mohammad Reza Nayeb 10031947532846002250 10031947532846002250 No Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Motahareh RouhparvarZamin 10031947532846002251 10031947532846002251 No Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Saeed Salimi 10031947532846002252 10031947532846002252 No Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Fahimeh Shojaeifar 10031947532846002253 10031947532846002253 Yes Research Center for Nursing and Midwifery Care, Comprehensive Research Institute for Maternal and Child Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran