Research in Health and Medical Sciences

en Evaluation of epidemiology, clinical signs, and laboratory factors in pregnant patients with COVID-19 admitted to Valiasr Hospital in Birjand from 2020 to 2021 Evaluation of epidemiology, clinical signs, and laboratory factors in pregnant patients with COVID-19 admitted to Valiasr Hospital in Birjand from 2020 to 2021 عمومى General Background: Pregnant women are one of the high-risk groups in the coronavirus crisis. Given the maternal physiologic and immune function changes during pregnancy, pregnant women may be at a higher risk of being infected with SARS-CoV-2 and developing more complicated clinical events. Methods: The cross-sectional study was conducted on all pregnant women with COVID-19 who were hospitalized in Valiasr Hospital in Birjand. People were included by census method and the sample size was estimated to be 205 people. The research tool included a researcher-made checklist including demographic characteristics, clinical symptoms, medical examinations, and paraclinical results. Results:. According to the results, the mean age of the mothers was 30.48 ± 5.32 years. The most common underlying diseases were hypothyroidism, gestational diabetes mellitus, hypertension and diabetes mellitus, respectively. Cough, myalgia, shortness of breath, fever, and nausea were the most common clinical symptoms observed in pregnant mothers with COVID-19. The results of inflammatory indices of ESR, and CRP were reported as 14.88 ± 30.52 mm/h, and 27.62 ± 34.30 mg/L, respectively. The mean length of hospitalization due to COVID-19 in pregnant mothers was 3.05 ± 3.17 days. The mortality of COVID-19 among pregnant mothers was only 1 person (0.5%). Conclusions: In conclusion, hypothyroidism was reported as the most common underlying disease in the studied pregnant women, which seems to be necessary to take measures to control this disease and prevent its adverse effects on the mother and the fetus.   Pregnant women are considered a high-risk group during the coronavirus crisis. Due to the physiological and immune system changes that occur during pregnancy, they may be more susceptible to SARS-CoV-2 infection and experience more severe clinical outcomes. A cross-sectional study was conducted on all pregnant women with COVID-19 who were hospitalized at Valiasr Hospital in Birjand. Participants were selected through a consus method, with a total sample size of 250 individuals. The research tool consisted of a researcherdeveloped checklist that includ demographic information, clinical symptoms, medical examinations, and paraclinical results. The average age of the mothers was 30.48 ± 5.32 years. The most common underlying conditions were hypothyroidism (12.7%), gestational diabetes mellitus (9.3%), hypertension (2.0%) and diabetes mellitus (1.5%). Common clinical symptoms observed in pregnant women with COVID-19 included cough (39.5%), myalgia (25.9%), shortness of breath (24.4%), fever (21.5%), and nausea (14.6%). Inflammatory markers such as ESR and CRP were reported as 14.88 ± 30.52 mm/h and 27.62 ± 34.30 mg/L, respectively. The average hospitalization duration for pregnant women with COVID-19 was 3.05 ± 3.17 days. The mortality rate among pregnant women with COVID-19 was only 1 person (0.5%). Hypothyroidism was identified as the most prevalent underlying condition among the pregnant women in this study. It is important to implement measures to manage this condition and prevent any negative impacts on both the mother and the fetus.   COVID-19, Pregnancy, Epidemiology, Clinical signs COVID-19, Pregnancy, Epidemiology, Clinical signs 23 34 http://jrhms.thums.ac.ir/browse.php?a_code=A-10-114-1&slc_lang=en&sid=1 Fatemeh Birjandi 10031947532846001014 10031947532846001014 No General Practitioner, Birjand University of Medical Sciences, Birjand, Iran Samaneh Bagherian 10031947532846001015 10031947532846001015 No Department of Operating Room, School of Paramedical, Geriatric Health Research Center, Birjand University of Medical Sciences, Birjand, Iran Masood Ziaee 10031947532846001016 10031947532846001016 No Department of Infectious Diseases, School of Medicine, Infectious Diseases Research Center, Birjand University of Medical Science, Birjand, Iran Najmeh Jahani njm.jahani@yahoo.com 10031947532846001017 10031947532846001017 Yes Department of Obstetrics and Gynecology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran